Preparative chromatographic grade acetonitrile

11/08/2022

Acetonitrile(cas75-05-8) is a widely used solvent in various analytical and preparative chromatographic techniques, such as high-performance liquid chromatography (HPLC), gas chromatography (GC), and supercritical fluid chromatography (SFC). It has several advantages over other common solvents, such as low viscosity, high polarity, low toxicity, and good compatibility with water and organic phases. However, not all acetonitrile products are suitable for chromatographic applications, as they may contain impurities that can interfere with the separation, detection, or quantification of the analytes. Therefore, it is important to choose a high-quality acetonitrile product that meets the specific requirements of your chromatographic method.

In this article, we will introduce you to our preparative chromatographic grade acetonitrile, a premium product that offers superior performance and reliability for your analytical needs. We will also discuss some of the features and benefits of using our product, as well as some tips on how to store and handle it properly.

What is Preparative Chromatographic Grade Acetonitrile?

Preparative chromatographic grade acetonitrile is a specially purified acetonitrile product that meets the highest standards of quality and purity for chromatographic applications. It is produced by a rigorous distillation process that removes any trace impurities, such as water, aldehydes, ketones, acids, bases, metals, and halides. It also undergoes strict quality control tests to ensure that it complies with the specifications of various pharmacopoeias and regulatory agencies, such as USP, EP, BP, JP, and FDA.

Our preparative chromatographic grade acetonitrile has the following characteristics:

High purity: >99.9%
Low water content: <0.05%
Low UV absorbance: <0.01 AU at 200-400 nm
Low residue on evaporation: <1 mg/L
Low acidity and alkalinity: <0.2 meq/kg
Low metal content: <0.1 ppm for each metal

Why Use Preparative Chromatographic Grade Acetonitrile?

Using our preparative chromatographic grade acetonitrile can offer you several benefits for your chromatographic applications, such as:

Improved separation efficiency: Our product has a low viscosity and a high polarity, which can enhance the solubility and elution of polar and non-polar compounds. It can also reduce the back pressure and increase the flow rate of your chromatographic system, resulting in faster and more efficient separations.
Enhanced detection sensitivity: Our product has a low UV absorbance and a low fluorescence background, which can improve the signal-to-noise ratio and the detection limit of your UV or fluorescence detectors. It can also reduce the interference from impurities and matrix effects, leading to more accurate and precise results.
Extended column life: Our product has a low water content and a low acidity and alkalinity, which can prevent the hydrolysis and degradation of your column packing material. It can also reduce the fouling and clogging of your column by impurities and particulates, prolonging the lifespan and performance of your column.
Reduced solvent consumption and waste generation: Our product has a high purity and a low residue on evaporation, which means that you can use less solvent for your chromatographic runs and generate less waste for disposal. This can save you time, money, and resources, as well as reduce the environmental impact of your laboratory activities.

How to Store and Handle Preparative Chromatographic Grade Acetonitrile?

To ensure the quality and stability of our preparative chromatographic grade acetonitrile, we recommend that you follow these guidelines for storing and handling it:

Store it in a cool, dry, and well-ventilated place away from heat sources, direct sunlight, oxidizing agents, acids, bases, metals, halogens, and flammable materials.
Keep it in its original container or in a suitable glass or stainless steel container with a tight-fitting cap. Do not use plastic or rubber containers or fittings, as they may leach impurities into the solvent or react with it.
Use it within one year of opening the container or within the expiration date indicated on the label. Do not use it if it shows signs of discoloration, cloudiness, precipitation, or odor change.
Before using it, check its appearance and purity by measuring its refractive index, specific gravity, water content, UV absorbance, residue on evaporation, acidity and alkalinity, and metal content. If any of these parameters are out of specification, do not use it.
When transferring it from one container to another or from one instrument to another, use clean glass or stainless steel syringes or pipettes. Do not use plastic or rubber syringes or pipettes, as they may introduce impurities or contaminants into the solvent or the sample.
When using it as a mobile phase or a sample solvent, degas it by sonication, vacuum, or helium sparging to remove any dissolved gases that may cause bubbles or noise in your chromatographic system.
When disposing of it, follow the local regulations and guidelines for hazardous waste management. Do not pour it down the drain or into the environment.

Conclusion

Preparative chromatographic grade acetonitrile is a high-quality solvent that can provide you with optimal performance and reliability for your analytical and preparative chromatographic applications. It has a high purity, a low water content, a low UV absorbance, a low residue on evaporation, a low acidity and alkalinity, and a low metal content. It can improve your separation efficiency, enhance your detection sensitivity, extend your column life, and reduce your solvent consumption and waste generation. It is easy to store and handle, as long as you follow the proper guidelines and precautions.

How to Buy Acetonitrile?

If you are looking for a reliable acetonitrile supplier in China, you can visit our SHANDONG QIBO NEW ENERGY CO., LTD. website www.qiboch.com. We have various grades and quantities of acetonitrile(cas75-05-8) available for sale. We also sell other industrial chemicals such as Cyclohexanone, Methylene Chlorid e, glacial acetic acid, ethanol, etc. We ship our products worldwide at competitive prices. Contact us today for a free quote.